Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. These side effects can range from being mild to severe. With this condition, you also have a low hemoglobin level. (For more information on Venofer, see the Injectafer vs. Venofer section above). You may wonder how Injectafer compares with other medications that are prescribed for similar uses. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Hes an expert in genetic testing, genetic analysis, andprecision medicine. There isnt a known interaction between Injectafer and alcohol. Does Venofer Vial interact with other drugs you are taking? It is usually given slowly over 2 to 5 minutes or as directed by your doctor. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. . Before taking Injectafer, talk with your doctor about your health history. Youll receive doses of Injectafer from a healthcare professional at a medical facility. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. Injectafer and Venofer are both brand-name drugs. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. These are not all of the side effects that may occur. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. It's a more immediate treatment than supplements or dietary changes. Venofer® (iron sucrose injection, USP) is available by prescription only. <> Consult your pharmacist or local waste disposal company. If either is present, do not use the liquid. Its possible that after getting two doses of Injectafer, your anemia may go away completely. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Serious side effects should be reported to a physician and/or PharmD for medical advice. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Your doctor will go over your
reese0809 1 yr. ago. Hemoglobin is a protein thats found in your RBCs. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. The following information describes dosages that are commonly used or recommended. Injectafer and Feraheme are both brand-name drugs. Consult the product instructions and your pharmacist for storage details. Details. The oral form of the drug, called sucroferric oxyhydroxide and used . If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Source: Wolters Kluwer Health. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). This treatment course is split into two doses of the drug, which are given at least 7 days apart. On day three I had a headache and felt heavy/exhausted, which lasted a few days. Mental healthdisorders like depression may requireantidepressantsto treat. This may be helped by giving the medication more slowly or at a lower dose. endobj In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. And Feraheme is approved for use in adults who have CKD who may or may not need dialysis. And these two doses need to be separated by at least 7 days. Check with your pharmacist if you have questions about the best way to throw out drugs. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. This can be very helpful in . Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. This is not a complete list of possible side effects. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. What Is the Cost of Whole Genome Sequencing (WGS)? This gives a total cumulative dose of 1,500 mg of Injectafer. However, consuming large amounts of alcohol can actually cause anemia in some people. . Iron infusion side effects vary depending on which form is being used. This medication is given by injection into a vein as directed by your doctor. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Its given by either intravenous (IV) infusion or slow IV injection. Your doctor will determine the best dosage to fit your needs. Amounts of iron ingested by the infant would be normal and are not expected to cause any adverse effects in breastfed infants. I actually was constipated after my 3rd but didn't think anything of it. A variety of tests can diagnose iron deficiency anemia. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. One study of just under 5000 HRT users found that 43% were affected. Pain, swelling, or redness at the injection site may occur. What is the latest research on the form of cancer Jimmy Carter has? (One treatment course includes two doses of the drug.) After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Tell your doctor if you are taking iron supplements or other iron-based oral medications. They can recommend appropriate treatment options. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. And this can lead to anemia, including IDA. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. pain in the arms or legs. These lists dont include all possible side effects. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. Below are examples of these side effects. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. This site is intended for use only by US patients. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. Theseside effectscan range from being mild tosevere. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. Hemoglobin is a protein thats found inside your red blood cells. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Injectafer is available only as a brand-name medication. But for other people, their anemia may come back after Injectafer treatment. Side effects like nausea and low blood pressure are common with most iron infusions. If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. However, many people have no side effects or only have minor side effects. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). Effectiveness of Injectafer compared with iron thats taken by mouth. endobj Depending on your anemia symptoms, your weight changes may be different than those described here. fever. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Talk with the doctor. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. Medically reviewed by Sanjai Sinha, MD. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. Its responsible for carrying oxygen throughout your body. Its not currently available in generic form. <> 1 0 obj For people with certain medical implants, such as pacemakers, an MRI may pose an . Side effectsare uncomfortable reactions to medications or drugs. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Generics tend to cost less than brand-name drugs. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: (IV iron is absorbed by the body more rapidly than oral iron.) For example: Say you weigh 105 pounds (about 48 kilograms). The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. This survey is being conducted by the WebMD marketing sciences department. (And Injectafer is used to treat IDA.) Theyll do this by checking certain blood tests. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. (A medication class describes a group of drugs that work in the same way.). TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. But for other people, their IDA returns after treatment with Injectafer. Ask your doctor or healthcare provider if Venofer is the right choice for you. With IV infusion, the drug is given as a slow drip into your vein over a period of time. % Your doctor will be able to see how Venofer is working by reviewing your blood tests. Most people will metabolize medication by half every time it circulates the body. Others last much longer (even a lifetime), which can be quite traumatizing to people. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Innovators Monograph Someside effectsare temporary or last as long as the person continues takingprescription medicine. Things to remember when you fill your prescription. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Mild side effects of Injectafer can include:*. For some people, it may be OK to continue taking a multivitamin that contains iron. You should always consult your doctor or another healthcare professional before taking any medication. In the US - Call your doctor for medical advice about side effects. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. This website is intended for use by US healthcare professionals only. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Why is the range so wide? People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. All of the people took iron by mouth for 2 weeks. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. Terminal half-life ranges from 7 to 12 hours. * This is a partial list of mild side effects from Injectafer. The benefit of treating your condition during pregnancy may outweigh any risks. Cardiovascular health: Insomnia linked to greater risk of heart attack. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Call your doctor for medical advice about side effects. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. It is very important that your doctor check you closely while you are receiving this medicine. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. Check with your pharmacist. Be ready to tell or show what was taken, how much, and when it happened.